Mth938 domain-containing protein (AAMDC)
Homo sapiens — UniProt Q9H7C9
Data last refreshed: (UniProt release unknown)
Key facts
Mth938 domain-containing protein (AAMDC) is a protein from Homo sapiens identified by UniProt accession Q9H7C9, 122 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H7C9; gene symbol AAMDC.
- Organism: Homo sapiens.
- Length: 122 amino acids.
- Top disease associations (Open Targets): platelet count, body height and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mth938 domain-containing protein |
|---|---|
| UniProt accession | Q9H7C9 |
| Gene | AAMDC |
| Organism | Homo sapiens |
| Length | 122 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- platelet count · score 0.39
- body height · score 0.33
- diastolic blood pressure · score 0.33
- mean platelet volume · score 0.21
- mean reticulocyte volume · score 0.17
- platelet component distribution width · score 0.12
- sex hormone-binding globulin measurement · score 0.08
- grip strength measurement · score 0.06
- handedness · score 0.05
- age at menarche · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7C9-F1 | alphafold | PREDICTED | 97.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7C9.
Amino-acid sequence (122 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AAMDC?
The strongest Open Targets associations for AAMDC are platelet count, body height, diastolic blood pressure, mean platelet volume and mean reticulocyte volume.
How long is the AAMDC protein?
The Homo sapiens AAMDC protein (UniProt Q9H7C9) is 122 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7C9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7C9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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