Tudor domain-containing protein 3 (TDRD3)
Homo sapiens — UniProt Q9H7E2
Data last refreshed: (UniProt release unknown)
Key facts
Tudor domain-containing protein 3 (TDRD3) is a protein from Homo sapiens identified by UniProt accession Q9H7E2, 651 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9H7E2; gene symbol TDRD3.
- Organism: Homo sapiens.
- Length: 651 amino acids.
- Top disease associations (Open Targets): age at menopause, menopause and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tudor domain-containing protein 3 |
|---|---|
| UniProt accession | Q9H7E2 |
| Gene | TDRD3 |
| Organism | Homo sapiens |
| Length | 651 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- age at menopause · score 0.35
- menopause · score 0.25
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
- common variable immunodeficiency · score 0.05
- combined immunodeficiency with skin granulomas · score 0.04
- severe combined immunodeficiency due to CTPS1 deficiency · score 0.04
- Transcobalamin deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7E2-F1 | alphafold | PREDICTED | 58.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7E2.
Amino-acid sequence (651 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TDRD3?
The strongest Open Targets associations for TDRD3 are age at menopause, menopause, attention deficit hyperactivity disorder, Tourette syndrome and schizophrenia 15.
How long is the TDRD3 protein?
The Homo sapiens TDRD3 protein (UniProt Q9H7E2) is 651 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7E2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7E2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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