UPF0488 protein C8orf33 (C8orf33)
Homo sapiens — UniProt Q9H7E9
Data last refreshed: (UniProt release unknown)
Key facts
UPF0488 protein C8orf33 (C8orf33) is a protein from Homo sapiens identified by UniProt accession Q9H7E9, 229 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9H7E9; gene symbol C8orf33.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and systemic juvenile idiopathic arthritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0488 protein C8orf33 |
|---|---|
| UniProt accession | Q9H7E9 |
| Gene | C8orf33 |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- hepatocellular carcinoma · score 0.04
- systemic juvenile idiopathic arthritis · score 0.01
- colorectal cancer · score 0.01
- hepatitis B virus induced hepatocellular carcinoma · score 0.01
- neoplasm · score 0.00
- cancer · score 0.00
- nasopharyngeal neoplasm · score 0.00
- breast cancer · score 0.00
- colorectal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7E9-F1 | alphafold | PREDICTED | 71.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7E9.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C8orf33?
The strongest Open Targets associations for C8orf33 are neurodegenerative disease, hepatocellular carcinoma, systemic juvenile idiopathic arthritis, colorectal cancer and hepatitis B virus induced hepatocellular carcinoma.
How long is the C8orf33 protein?
The Homo sapiens C8orf33 protein (UniProt Q9H7E9) is 229 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7E9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7E9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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