Polyamine-transporting ATPase 13A3 (ATP13A3)
Homo sapiens — UniProt Q9H7F0
Data last refreshed: (UniProt release unknown)
Key facts
Polyamine-transporting ATPase 13A3 (ATP13A3) is a protein from Homo sapiens identified by UniProt accession Q9H7F0, 1226 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9H7F0; gene symbol ATP13A3.
- Organism: Homo sapiens.
- Length: 1226 amino acids.
- Top disease associations (Open Targets): pulmonary hypertension, primary, autosomal recessive, pulmonary arterial hypertension and heritable pulmonary arterial hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyamine-transporting ATPase 13A3 |
|---|---|
| UniProt accession | Q9H7F0 |
| Gene | ATP13A3 |
| Organism | Homo sapiens |
| Length | 1226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- pulmonary hypertension, primary, autosomal recessive · score 0.65
- pulmonary arterial hypertension · score 0.59
- heritable pulmonary arterial hypertension · score 0.37
- lymphocyte count · score 0.29
- erythrocyte count · score 0.18
- mean platelet volume · score 0.16
- gut microbiome measurement · score 0.16
- hip circumference · score 0.12
- basophil count · score 0.09
- red blood cell density measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7F0-F1 | alphafold | PREDICTED | 77.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7F0.
Amino-acid sequence (1226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP13A3?
The strongest Open Targets associations for ATP13A3 are pulmonary hypertension, primary, autosomal recessive, pulmonary arterial hypertension, heritable pulmonary arterial hypertension, lymphocyte count and erythrocyte count.
How long is the ATP13A3 protein?
The Homo sapiens ATP13A3 protein (UniProt Q9H7F0) is 1226 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7F0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7F0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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