Ribosome assembly protein METTL17, mitochondrial (METTL17)
Homo sapiens — UniProt Q9H7H0
Data last refreshed: (UniProt release unknown)
Key facts
Ribosome assembly protein METTL17, mitochondrial (METTL17) is a protein from Homo sapiens identified by UniProt accession Q9H7H0, 456 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9H7H0; gene symbol METTL17.
- Organism: Homo sapiens.
- Length: 456 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosome assembly protein METTL17, mitochondrial |
|---|---|
| UniProt accession | Q9H7H0 |
| Gene | METTL17 |
| Organism | Homo sapiens |
| Length | 456 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- cancer · score 0.07
- neoplasm · score 0.07
- carcinoma · score 0.01
- adenoma · score 0.01
- Pick disease · score 0.01
- colitis · score 0.00
- atrial fibrillation · score 0.00
- mitochondrial disease · score 0.00
- progressive supranuclear palsy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7H0-F1 | alphafold | PREDICTED | 85.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7H0.
Amino-acid sequence (456 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with METTL17?
The strongest Open Targets associations for METTL17 are neurodegenerative disease, cancer, neoplasm, carcinoma and adenoma.
How long is the METTL17 protein?
The Homo sapiens METTL17 protein (UniProt Q9H7H0) is 456 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7H0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7H0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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