Protein phosphatase 1 regulatory subunit 3E (PPP1R3E)
Homo sapiens — UniProt Q9H7J1
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 3E (PPP1R3E) is a protein from Homo sapiens identified by UniProt accession Q9H7J1, 279 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9H7J1; gene symbol PPP1R3E.
- Organism: Homo sapiens.
- Length: 279 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroinflammatory disorder and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 3E |
|---|---|
| UniProt accession | Q9H7J1 |
| Gene | PPP1R3E |
| Organism | Homo sapiens |
| Length | 279 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- neuroinflammatory disorder · score 0.34
- reticulocyte measurement · score 0.10
- reticulocyte count · score 0.08
- body weight · score 0.06
- myeloid white cell count · score 0.06
- sex hormone-binding globulin measurement · score 0.06
- body height · score 0.05
- mean platelet volume · score 0.05
- testosterone measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7J1-F1 | alphafold | PREDICTED | 72.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7J1.
Amino-acid sequence (279 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R3E?
The strongest Open Targets associations for PPP1R3E are neurodegenerative disease, neuroinflammatory disorder, reticulocyte measurement, reticulocyte count and body weight.
How long is the PPP1R3E protein?
The Homo sapiens PPP1R3E protein (UniProt Q9H7J1) is 279 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7J1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7J1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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