Sin3 histone deacetylase corepressor complex component SDS3 (SUDS3)
Homo sapiens — UniProt Q9H7L9
Data last refreshed: (UniProt release unknown)
Key facts
Sin3 histone deacetylase corepressor complex component SDS3 (SUDS3) is a protein from Homo sapiens identified by UniProt accession Q9H7L9, 328 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H7L9; gene symbol SUDS3.
- Organism: Homo sapiens.
- Length: 328 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroticism measurement and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sin3 histone deacetylase corepressor complex component SDS3 |
|---|---|
| UniProt accession | Q9H7L9 |
| Gene | SUDS3 |
| Organism | Homo sapiens |
| Length | 328 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- neuroticism measurement · score 0.31
- breast adenocarcinoma · score 0.26
- glioblastoma multiforme · score 0.23
- acute myeloid leukemia · score 0.22
- wellbeing measurement · score 0.22
- loneliness measurement · score 0.16
- type 1 diabetes mellitus · score 0.16
- neurofibrillary tangles measurement · score 0.16
- PHF-tau measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7L9-F1 | alphafold | PREDICTED | 78.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7L9.
Amino-acid sequence (328 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUDS3?
The strongest Open Targets associations for SUDS3 are neurodegenerative disease, neuroticism measurement, breast adenocarcinoma, glioblastoma multiforme and acute myeloid leukemia.
How long is the SUDS3 protein?
The Homo sapiens SUDS3 protein (UniProt Q9H7L9) is 328 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7L9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7L9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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