Zinc finger SWIM domain-containing protein 4 (ZSWIM4)
Homo sapiens — UniProt Q9H7M6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger SWIM domain-containing protein 4 (ZSWIM4) is a protein from Homo sapiens identified by UniProt accession Q9H7M6, 989 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9H7M6; gene symbol ZSWIM4.
- Organism: Homo sapiens.
- Length: 989 amino acids.
- Top disease associations (Open Targets): lymphocyte count, leukocyte count and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger SWIM domain-containing protein 4 |
|---|---|
| UniProt accession | Q9H7M6 |
| Gene | ZSWIM4 |
| Organism | Homo sapiens |
| Length | 989 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.36
- leukocyte count · score 0.33
- monocyte count · score 0.30
- lymphocyte percentage of leukocytes · score 0.29
- FEV/FVC ratio · score 0.29
- neutrophil percentage of leukocytes · score 0.24
- platelet-to-lymphocyte ratio · score 0.23
- grip strength measurement · score 0.22
- myeloid white cell count · score 0.19
- waist-hip ratio · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7M6-F1 | alphafold | PREDICTED | 83.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7M6.
Amino-acid sequence (989 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZSWIM4?
The strongest Open Targets associations for ZSWIM4 are lymphocyte count, leukocyte count, monocyte count, lymphocyte percentage of leukocytes and FEV/FVC ratio.
How long is the ZSWIM4 protein?
The Homo sapiens ZSWIM4 protein (UniProt Q9H7M6) is 989 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7M6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7M6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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