Splicing factor, arginine/serine-rich 19 (SCAF1)
Homo sapiens — UniProt Q9H7N4
Data last refreshed: (UniProt release unknown)
Key facts
Splicing factor, arginine/serine-rich 19 (SCAF1) is a protein from Homo sapiens identified by UniProt accession Q9H7N4, 1312 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9H7N4; gene symbol SCAF1.
- Organism: Homo sapiens.
- Length: 1312 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum albumin measurement and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Splicing factor, arginine/serine-rich 19 |
|---|---|
| UniProt accession | Q9H7N4 |
| Gene | SCAF1 |
| Organism | Homo sapiens |
| Length | 1312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- serum albumin measurement · score 0.23
- alkaline phosphatase measurement · score 0.23
- total blood protein measurement · score 0.23
- calcium measurement · score 0.23
- heel bone mineral density · score 0.23
- body height · score 0.20
- basal cell carcinoma · score 0.20
- high density lipoprotein cholesterol measurement · score 0.17
- mean corpuscular hemoglobin · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7N4-F1 | alphafold | PREDICTED | 46.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7N4.
Amino-acid sequence (1312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCAF1?
The strongest Open Targets associations for SCAF1 are neurodegenerative disease, serum albumin measurement, alkaline phosphatase measurement, total blood protein measurement and calcium measurement.
How long is the SCAF1 protein?
The Homo sapiens SCAF1 protein (UniProt Q9H7N4) is 1312 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7N4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7N4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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