Multivesicular body subunit 12B (MVB12B)
Homo sapiens — UniProt Q9H7P6
Data last refreshed: (UniProt release unknown)
Key facts
Multivesicular body subunit 12B (MVB12B) is a protein from Homo sapiens identified by UniProt accession Q9H7P6, 319 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9H7P6; gene symbol MVB12B.
- Organism: Homo sapiens.
- Length: 319 amino acids.
- Top disease associations (Open Targets): HIV infection, viral disease and malaria.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Multivesicular body subunit 12B |
|---|---|
| UniProt accession | Q9H7P6 |
| Gene | MVB12B |
| Organism | Homo sapiens |
| Length | 319 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.53
- viral disease · score 0.46
- malaria · score 0.39
- balding measurement · score 0.33
- risk-taking behaviour · score 0.33
- Abnormality of refraction · score 0.33
- refractive error · score 0.33
- age at onset · score 0.33
- Myopia · score 0.33
- intraocular pressure measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7P6-F1 | alphafold | PREDICTED | 76.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7P6.
Amino-acid sequence (319 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MVB12B?
The strongest Open Targets associations for MVB12B are HIV infection, viral disease, malaria, balding measurement and risk-taking behaviour.
How long is the MVB12B protein?
The Homo sapiens MVB12B protein (UniProt Q9H7P6) is 319 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7P6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7P6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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