Zinc finger protein 442 (ZNF442)
Homo sapiens — UniProt Q9H7R0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 442 (ZNF442) is a protein from Homo sapiens identified by UniProt accession Q9H7R0, 627 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q9H7R0; gene symbol ZNF442.
- Organism: Homo sapiens.
- Length: 627 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, testosterone measurement and Down syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 442 |
|---|---|
| UniProt accession | Q9H7R0 |
| Gene | ZNF442 |
| Organism | Homo sapiens |
| Length | 627 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- testosterone measurement · score 0.06
- Down syndrome · score 0.04
- triple-negative breast cancer · score 0.00
- breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7R0-F1 | alphafold | PREDICTED | 70.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7R0.
Amino-acid sequence (627 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF442?
The strongest Open Targets associations for ZNF442 are neurodegenerative disease, testosterone measurement, Down syndrome, triple-negative breast cancer and breast cancer.
How long is the ZNF442 protein?
The Homo sapiens ZNF442 protein (UniProt Q9H7R0) is 627 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7R0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7R0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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