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Zinc finger protein 703 (ZNF703)

Homo sapiens — UniProt Q9H7S9

Gene: ZNF703Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 703 (ZNF703) is a protein from Homo sapiens identified by UniProt accession Q9H7S9, 590 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

  • UniProt accession: Q9H7S9; gene symbol ZNF703.
  • Organism: Homo sapiens.
  • Length: 590 amino acids.
  • Top disease associations (Open Targets): body height, triglyceride measurement and type 2 diabetes mellitus.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 703
UniProt accessionQ9H7S9
GeneZNF703
OrganismHomo sapiens
Length590 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • body height · score 0.33
  • triglyceride measurement · score 0.32
  • type 2 diabetes mellitus · score 0.31
  • testosterone measurement · score 0.28
  • reticulocyte count · score 0.26
  • leukocyte count · score 0.25
  • lymphocyte count · score 0.25
  • neoplasm · score 0.11
  • breast cancer · score 0.08
  • cholangiocarcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H7S9-F1alphafoldPREDICTED50.24—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7S9.

Amino-acid sequence (590 residues)

MSDSPAGSNP RTPESSGSGS GGGGKRPAVP AAVSLLPPAD PLRQANRLPI RVLKMLSAHT GHLLHPEYLQ PLSSTPVSPI ELDAKKSPLA LLAQTCSQIG KPDPPPSSKL NSVAAAANGL GAEKDPGRSA PGAASAAAAL KQLGDSPAED KSSFKPYSKG SGGGDSRKDS GSSSVSSTSS SSSSSPGDKA GFRVPSAACP PFPPHGAPVS ASSSSSSPGG SRGGSPHHSD CKNGGGVGGG ELDKKDQEPK PSPEPAAVSR GGGGEPGAHG GAESGASGRK SEPPSALVGA GHVAPVSPYK PGHSVFPLPP SSIGYHGSIV GAYAGYPSQF VPGLDPSKSG LVGGQLSGGL GLPPGKPPSS SPLTGASPPS FLQGLCRDPY CLGGYHGASH LGGSSCSTCS AHDPAGPSLK AGGYPLVYPG HPLQPAALSS SAAQAALPGH PLYTYGFMLQ NEPLPHSCNW VAASGPCDKR FATSEELLSH LRTHTALPGA EKLLAAYPGA SGLGSAAAAA AAAASCHLHL PPPAAPGSPG SLSLRNPHTL GLSRYHPYGK SHLSTAGGLA VPSLPTAGPY YSPYALYGQR LASASALGYQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF703?

The strongest Open Targets associations for ZNF703 are body height, triglyceride measurement, type 2 diabetes mellitus, testosterone measurement and reticulocyte count.

How long is the ZNF703 protein?

The Homo sapiens ZNF703 protein (UniProt Q9H7S9) is 590 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H7S9
GeneZNF703
OrganismHomo sapiens
Length590
Binders0
Diseases62
View on UniProt