Cation channel sperm-associated auxiliary subunit beta (CATSPERB)
Homo sapiens — UniProt Q9H7T0
Data last refreshed: (UniProt release unknown)
Key facts
Cation channel sperm-associated auxiliary subunit beta (CATSPERB) is a protein from Homo sapiens identified by UniProt accession Q9H7T0, 1116 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9H7T0; gene symbol CATSPERB.
- Organism: Homo sapiens.
- Length: 1116 amino acids.
- Target class: Ion channel.
- Top disease associations (Open Targets): mean platelet volume, body height and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cation channel sperm-associated auxiliary subunit beta |
|---|---|
| UniProt accession | Q9H7T0 |
| Gene | CATSPERB |
| Organism | Homo sapiens |
| Length | 1116 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Ion channel (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.45
- body height · score 0.38
- platelet component distribution width · score 0.38
- venous thromboembolism · score 0.32
- platelet count · score 0.30
- cutaneous melanoma · score 0.25
- lung adenocarcinoma · score 0.23
- calcium measurement · score 0.23
- factor VIII measurement · score 0.20
- brain volume measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7T0-F1 | alphafold | PREDICTED | 85.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7T0.
Amino-acid sequence (1116 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CATSPERB?
The strongest Open Targets associations for CATSPERB are mean platelet volume, body height, platelet component distribution width, venous thromboembolism and platelet count.
How long is the CATSPERB protein?
The Homo sapiens CATSPERB protein (UniProt Q9H7T0) is 1116 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7T0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7T0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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