Serine-rich coiled-coil domain-containing protein 2 (CCSER2)
Homo sapiens — UniProt Q9H7U1
Data last refreshed: (UniProt release unknown)
Key facts
Serine-rich coiled-coil domain-containing protein 2 (CCSER2) is a protein from Homo sapiens identified by UniProt accession Q9H7U1, 834 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H7U1; gene symbol CCSER2.
- Organism: Homo sapiens.
- Length: 834 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, triglyceride measurement and response to selective serotonin reuptake inhibitor.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine-rich coiled-coil domain-containing protein 2 |
|---|---|
| UniProt accession | Q9H7U1 |
| Gene | CCSER2 |
| Organism | Homo sapiens |
| Length | 834 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.32
- triglyceride measurement · score 0.25
- response to selective serotonin reuptake inhibitor · score 0.25
- neurofibrillary tangles measurement · score 0.22
- osteomyelitis · score 0.18
- protein measurement · score 0.13
- influenza A (H1N1) · score 0.04
- lissencephaly type 1 due to doublecortin gene mutation · score 0.03
- Genetic central nervous system malformation · score 0.03
- sub-cortical nodular heterotopia · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7U1-F1 | alphafold | PREDICTED | 48.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7U1.
Amino-acid sequence (834 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCSER2?
The strongest Open Targets associations for CCSER2 are FEV/FVC ratio, triglyceride measurement, response to selective serotonin reuptake inhibitor, neurofibrillary tangles measurement and osteomyelitis.
How long is the CCSER2 protein?
The Homo sapiens CCSER2 protein (UniProt Q9H7U1) is 834 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7U1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7U1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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