Synapse differentiation-inducing gene protein 1 (SYNDIG1)
Homo sapiens — UniProt Q9H7V2
Data last refreshed: (UniProt release unknown)
Key facts
Synapse differentiation-inducing gene protein 1 (SYNDIG1) is a protein from Homo sapiens identified by UniProt accession Q9H7V2, 258 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9H7V2; gene symbol SYNDIG1.
- Organism: Homo sapiens.
- Length: 258 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, haptoglobin measurement and adenomatous colon polyp.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synapse differentiation-inducing gene protein 1 |
|---|---|
| UniProt accession | Q9H7V2 |
| Gene | SYNDIG1 |
| Organism | Homo sapiens |
| Length | 258 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- haptoglobin measurement · score 0.15
- adenomatous colon polyp · score 0.12
- lean body mass · score 0.06
- cystatin C measurement · score 0.05
- body weight · score 0.04
- breast carcinoma · score 0.04
- waist circumference · score 0.03
- alcohol consumption measurement · score 0.03
- atypical teratoid rhabdoid tumor · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7V2-F1 | alphafold | PREDICTED | 54.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7V2.
Amino-acid sequence (258 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYNDIG1?
The strongest Open Targets associations for SYNDIG1 are neurodegenerative disease, haptoglobin measurement, adenomatous colon polyp, lean body mass and cystatin C measurement.
How long is the SYNDIG1 protein?
The Homo sapiens SYNDIG1 protein (UniProt Q9H7V2) is 258 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7V2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7V2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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