Required for drug-induced death protein 1 (C1orf115)
Homo sapiens — UniProt Q9H7X2
Data last refreshed: (UniProt release unknown)
Key facts
Required for drug-induced death protein 1 (C1orf115) is a protein from Homo sapiens identified by UniProt accession Q9H7X2, 142 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9H7X2; gene symbol C1orf115.
- Organism: Homo sapiens.
- Length: 142 amino acids.
- Top disease associations (Open Targets): bilirubin measurement, BMI-adjusted waist circumference and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Required for drug-induced death protein 1 |
|---|---|
| UniProt accession | Q9H7X2 |
| Gene | C1orf115 |
| Organism | Homo sapiens |
| Length | 142 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.06
- BMI-adjusted waist circumference · score 0.06
- diastolic blood pressure · score 0.06
- body height · score 0.05
- BMI-adjusted waist-hip ratio · score 0.05
- mean corpuscular volume · score 0.04
- glioblastoma multiforme · score 0.04
- waist-hip ratio · score 0.04
- Barrett's esophagus · score 0.04
- high density lipoprotein cholesterol measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7X2-F1 | alphafold | PREDICTED | 63.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7X2.
Amino-acid sequence (142 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf115?
The strongest Open Targets associations for C1orf115 are bilirubin measurement, BMI-adjusted waist circumference, diastolic blood pressure, body height and BMI-adjusted waist-hip ratio.
How long is the C1orf115 protein?
The Homo sapiens C1orf115 protein (UniProt Q9H7X2) is 142 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7X2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7X2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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