Intraflagellar transport protein 22 homolog (IFT22)
Homo sapiens — UniProt Q9H7X7
Data last refreshed: (UniProt release unknown)
Key facts
Intraflagellar transport protein 22 homolog (IFT22) is a protein from Homo sapiens identified by UniProt accession Q9H7X7, 185 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9H7X7; gene symbol IFT22.
- Organism: Homo sapiens.
- Length: 185 amino acids.
- Top disease associations (Open Targets): rheumatoid arthritis, refractive error measurement and cortical thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Intraflagellar transport protein 22 homolog |
|---|---|
| UniProt accession | Q9H7X7 |
| Gene | IFT22 |
| Organism | Homo sapiens |
| Length | 185 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.18
- refractive error measurement · score 0.03
- cortical thickness · score 0.03
- response to antidepressant · score 0.02
- hemoglobin measurement · score 0.02
- Abnormal sperm morphology · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- Jeune syndrome · score 0.00
- oral squamous cell carcinoma · score 0.00
- Alzheimer disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7X7-F1 | alphafold | PREDICTED | 91.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7X7.
Amino-acid sequence (185 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IFT22?
The strongest Open Targets associations for IFT22 are rheumatoid arthritis, refractive error measurement, cortical thickness, response to antidepressant and hemoglobin measurement.
How long is the IFT22 protein?
The Homo sapiens IFT22 protein (UniProt Q9H7X7) is 185 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7X7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7X7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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