Divergent protein kinase domain 2B (DIPK2B)
Homo sapiens — UniProt Q9H7Y0
Data last refreshed: (UniProt release unknown)
Key facts
Divergent protein kinase domain 2B (DIPK2B) is a protein from Homo sapiens identified by UniProt accession Q9H7Y0, 433 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9H7Y0; gene symbol DIPK2B.
- Organism: Homo sapiens.
- Length: 433 amino acids.
- Top disease associations (Open Targets): Uterine leiomyoma, vaginal discharge and fragile X syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Divergent protein kinase domain 2B |
|---|---|
| UniProt accession | Q9H7Y0 |
| Gene | DIPK2B |
| Organism | Homo sapiens |
| Length | 433 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- Uterine leiomyoma · score 0.14
- vaginal discharge · score 0.14
- fragile X syndrome · score 0.01
- Autism · score 0.01
- nervous system disease · score 0.01
- lung adenocarcinoma · score 0.01
- endometrial carcinoma · score 0.00
- cancer · score 0.00
- Kabuki syndrome · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7Y0-F1 | alphafold | PREDICTED | 83.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7Y0.
Amino-acid sequence (433 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DIPK2B?
The strongest Open Targets associations for DIPK2B are Uterine leiomyoma, vaginal discharge, fragile X syndrome, Autism and nervous system disease.
How long is the DIPK2B protein?
The Homo sapiens DIPK2B protein (UniProt Q9H7Y0) is 433 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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