DnaJ homolog subfamily C member 18 (DNAJC18)
Homo sapiens — UniProt Q9H819
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 18 (DNAJC18) is a protein from Homo sapiens identified by UniProt accession Q9H819, 358 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9H819; gene symbol DNAJC18.
- Organism: Homo sapiens.
- Length: 358 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, electrocardiography and viral load.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 18 |
|---|---|
| UniProt accession | Q9H819 |
| Gene | DNAJC18 |
| Organism | Homo sapiens |
| Length | 358 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.28
- electrocardiography · score 0.17
- viral load · score 0.15
- hypertrophic cardiomyopathy · score 0.14
- appendicular lean mass · score 0.05
- creatinine measurement · score 0.03
- glomerular filtration rate · score 0.02
- urate measurement · score 0.02
- Abnormal sperm morphology · score 0.01
- infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H819-F1 | alphafold | PREDICTED | 71.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H819.
Amino-acid sequence (358 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC18?
The strongest Open Targets associations for DNAJC18 are systolic blood pressure, electrocardiography, viral load, hypertrophic cardiomyopathy and appendicular lean mass.
How long is the DNAJC18 protein?
The Homo sapiens DNAJC18 protein (UniProt Q9H819) is 358 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H819 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H819 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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