Gem-associated protein 7 (GEMIN7)
Homo sapiens — UniProt Q9H840
Data last refreshed: (UniProt release unknown)
Key facts
Gem-associated protein 7 (GEMIN7) is a protein from Homo sapiens identified by UniProt accession Q9H840, 131 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9H840; gene symbol GEMIN7.
- Organism: Homo sapiens.
- Length: 131 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monocyte percentage of leukocytes and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gem-associated protein 7 |
|---|---|
| UniProt accession | Q9H840 |
| Gene | GEMIN7 |
| Organism | Homo sapiens |
| Length | 131 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- monocyte percentage of leukocytes · score 0.03
- infect · score 0.03
- infection · score 0.03
- monocyte count · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- bladder transitional cell carcinoma · score 0.01
- severe malarial anemia · score 0.00
- parkinsonism-dystonia, infantile · score 0.00
- Infantile dystonia-parkinsonism · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H840-F1 | alphafold | PREDICTED | 80.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H840.
Amino-acid sequence (131 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GEMIN7?
The strongest Open Targets associations for GEMIN7 are neurodegenerative disease, monocyte percentage of leukocytes, infect, infection and monocyte count.
How long is the GEMIN7 protein?
The Homo sapiens GEMIN7 protein (UniProt Q9H840) is 131 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H840 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H840 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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