NIPA-like protein 2 (NIPAL2)
Homo sapiens — UniProt Q9H841
Data last refreshed: (UniProt release unknown)
Key facts
NIPA-like protein 2 (NIPAL2) is a protein from Homo sapiens identified by UniProt accession Q9H841, 383 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9H841; gene symbol NIPAL2.
- Organism: Homo sapiens.
- Length: 383 amino acids.
- Top disease associations (Open Targets): upper face morphology measurement, systolic blood pressure and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NIPA-like protein 2 |
|---|---|
| UniProt accession | Q9H841 |
| Gene | NIPAL2 |
| Organism | Homo sapiens |
| Length | 383 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- upper face morphology measurement · score 0.30
- systolic blood pressure · score 0.29
- appendicular lean mass · score 0.25
- susceptibility to childhood ear infection measurement · score 0.11
- tuberculosis · score 0.01
- Pick disease · score 0.01
- acute lymphoblastic leukemia · score 0.01
- pituitary cancer · score 0.00
- clear cell renal carcinoma · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H841-F1 | alphafold | PREDICTED | 79.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H841.
Amino-acid sequence (383 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NIPAL2?
The strongest Open Targets associations for NIPAL2 are upper face morphology measurement, systolic blood pressure, appendicular lean mass, susceptibility to childhood ear infection measurement and tuberculosis.
How long is the NIPAL2 protein?
The Homo sapiens NIPAL2 protein (UniProt Q9H841) is 383 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H841 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H841 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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