Complex I assembly factor ACAD9, mitochondrial (ACAD9)
Homo sapiens — UniProt Q9H845
Data last refreshed: (UniProt release unknown)
Key facts
Complex I assembly factor ACAD9, mitochondrial (ACAD9) is a protein from Homo sapiens identified by UniProt accession Q9H845, 621 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9H845; gene symbol ACAD9.
- Organism: Homo sapiens.
- Length: 621 amino acids.
- Top disease associations (Open Targets): acyl-CoA dehydrogenase 9 deficiency, mitochondrial complex I deficiency and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complex I assembly factor ACAD9, mitochondrial |
|---|---|
| UniProt accession | Q9H845 |
| Gene | ACAD9 |
| Organism | Homo sapiens |
| Length | 621 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- acyl-CoA dehydrogenase 9 deficiency · score 0.85
- mitochondrial complex I deficiency · score 0.65
- neurodegenerative disease · score 0.52
- hypophosphatasia · score 0.27
- lysosomal storage disease · score 0.22
- genetic disorder · score 0.19
- myeloid white cell count · score 0.19
- leukocyte count · score 0.12
- BMI-adjusted hip circumference · score 0.08
- self reported educational attainment · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H845-F1 | alphafold | PREDICTED | 91.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H845.
Amino-acid sequence (621 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACAD9?
The strongest Open Targets associations for ACAD9 are acyl-CoA dehydrogenase 9 deficiency, mitochondrial complex I deficiency, neurodegenerative disease, hypophosphatasia and lysosomal storage disease.
How long is the ACAD9 protein?
The Homo sapiens ACAD9 protein (UniProt Q9H845) is 621 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H845 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H845 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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