Tubulin-like protein alpha-4B (TUBA4B)
Homo sapiens — UniProt Q9H853
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin-like protein alpha-4B (TUBA4B) is a protein from Homo sapiens identified by UniProt accession Q9H853, 241 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9H853; gene symbol TUBA4B.
- Organism: Homo sapiens.
- Length: 241 amino acids.
- Top disease associations (Open Targets): viral disease, platelet component distribution width and ptosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin-like protein alpha-4B |
|---|---|
| UniProt accession | Q9H853 |
| Gene | TUBA4B |
| Organism | Homo sapiens |
| Length | 241 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- viral disease · score 0.46
- platelet component distribution width · score 0.15
- ptosis · score 0.12
- mean platelet volume · score 0.08
- gonorrhea · score 0.08
- lymphocyte percentage of leukocytes · score 0.06
- lymphocyte count · score 0.06
- reticulocyte count · score 0.05
- low density lipoprotein cholesterol measurement · score 0.04
- triglyceride measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H853-F1 | alphafold | PREDICTED | 72.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H853.
Amino-acid sequence (241 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TUBA4B?
The strongest Open Targets associations for TUBA4B are viral disease, platelet component distribution width, ptosis, mean platelet volume and gonorrhea.
How long is the TUBA4B protein?
The Homo sapiens TUBA4B protein (UniProt Q9H853) is 241 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H853 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H853 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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