YY1-associated protein 1 (YY1AP1)
Homo sapiens — UniProt Q9H869
Data last refreshed: (UniProt release unknown)
Key facts
YY1-associated protein 1 (YY1AP1) is a protein from Homo sapiens identified by UniProt accession Q9H869, 796 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.
- UniProt accession: Q9H869; gene symbol YY1AP1.
- Organism: Homo sapiens.
- Length: 796 amino acids.
- Top disease associations (Open Targets): grange syndrome, neurodegenerative disease and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | YY1-associated protein 1 |
|---|---|
| UniProt accession | Q9H869 |
| Gene | YY1AP1 |
| Organism | Homo sapiens |
| Length | 796 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (178)
Diseases linked to this target (Open Targets).
- grange syndrome · score 0.69
- neurodegenerative disease · score 0.23
- genetic disorder · score 0.19
- mathematical ability · score 0.10
- neutrophil count · score 0.09
- body mass index · score 0.08
- hepatocellular carcinoma · score 0.07
- testosterone measurement · score 0.07
- body weight · score 0.07
- vitamin D measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H869-F1 | alphafold | PREDICTED | 53.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H869.
Amino-acid sequence (796 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with YY1AP1?
The strongest Open Targets associations for YY1AP1 are grange syndrome, neurodegenerative disease, genetic disorder, mathematical ability and neutrophil count.
How long is the YY1AP1 protein?
The Homo sapiens YY1AP1 protein (UniProt Q9H869) is 796 amino acids long.
Browse: Targets: Y · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H869 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H869 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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