E3 ubiquitin-protein transferase RMND5A (RMND5A)
Homo sapiens — UniProt Q9H871
Data last refreshed: (UniProt release unknown)
Key facts
E3 ubiquitin-protein transferase RMND5A (RMND5A) is a protein from Homo sapiens identified by UniProt accession Q9H871, 391 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q9H871; gene symbol RMND5A.
- Organism: Homo sapiens.
- Length: 391 amino acids.
- Top disease associations (Open Targets): reticulocyte count, mean corpuscular volume and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | E3 ubiquitin-protein transferase RMND5A |
|---|---|
| UniProt accession | Q9H871 |
| Gene | RMND5A |
| Organism | Homo sapiens |
| Length | 391 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.34
- mean corpuscular volume · score 0.34
- mean corpuscular hemoglobin concentration · score 0.31
- mean corpuscular hemoglobin · score 0.29
- reticulocyte measurement · score 0.28
- Immature Reticulocyte Fraction Measurement · score 0.27
- blood protein measurement · score 0.19
- progressive supranuclear palsy · score 0.07
- pancreatic adenocarcinoma · score 0.06
- oral squamous cell carcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H871-F1 | alphafold | PREDICTED | 89.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H871.
Amino-acid sequence (391 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RMND5A?
The strongest Open Targets associations for RMND5A are reticulocyte count, mean corpuscular volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin and reticulocyte measurement.
How long is the RMND5A protein?
The Homo sapiens RMND5A protein (UniProt Q9H871) is 391 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H871 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H871 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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