PRKR-interacting protein 1 (PRKRIP1)
Homo sapiens — UniProt Q9H875
Data last refreshed: (UniProt release unknown)
Key facts
PRKR-interacting protein 1 (PRKRIP1) is a protein from Homo sapiens identified by UniProt accession Q9H875, 184 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9H875; gene symbol PRKRIP1.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): insomnia measurement, chronotype measurement and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PRKR-interacting protein 1 |
|---|---|
| UniProt accession | Q9H875 |
| Gene | PRKRIP1 |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- insomnia measurement · score 0.27
- chronotype measurement · score 0.21
- diabetes mellitus · score 0.04
- type 2 diabetes mellitus · score 0.04
- circadian rhythm · score 0.02
- mean platelet volume · score 0.02
- blood phosphate measurement · score 0.02
- platelet component distribution width · score 0.02
- BMI-adjusted waist-hip ratio · score 0.02
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H875-F1 | alphafold | PREDICTED | 80.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H875.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRKRIP1?
The strongest Open Targets associations for PRKRIP1 are insomnia measurement, chronotype measurement, diabetes mellitus, type 2 diabetes mellitus and circadian rhythm.
How long is the PRKRIP1 protein?
The Homo sapiens PRKRIP1 protein (UniProt Q9H875) is 184 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H875 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H875 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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