Zinc finger matrin-type protein 4 (ZMAT4)
Homo sapiens — UniProt Q9H898
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger matrin-type protein 4 (ZMAT4) is a protein from Homo sapiens identified by UniProt accession Q9H898, 229 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9H898; gene symbol ZMAT4.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): Myopia, refractive error and waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger matrin-type protein 4 |
|---|---|
| UniProt accession | Q9H898 |
| Gene | ZMAT4 |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- Myopia · score 0.46
- refractive error · score 0.45
- waist circumference · score 0.40
- age at onset · score 0.40
- Abnormality of refraction · score 0.39
- refractive error measurement · score 0.39
- bone density · score 0.36
- self reported educational attainment · score 0.31
- Hypermetropia · score 0.29
- fasting blood glucose measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H898-F1 | alphafold | PREDICTED | 73.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H898.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZMAT4?
The strongest Open Targets associations for ZMAT4 are Myopia, refractive error, waist circumference, age at onset and Abnormality of refraction.
How long is the ZMAT4 protein?
The Homo sapiens ZMAT4 protein (UniProt Q9H898) is 229 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H898 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H898 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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