Zinc finger protein 430 (ZNF430)
Homo sapiens — UniProt Q9H8G1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 430 (ZNF430) is a protein from Homo sapiens identified by UniProt accession Q9H8G1, 570 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9H8G1; gene symbol ZNF430.
- Organism: Homo sapiens.
- Length: 570 amino acids.
- Top disease associations (Open Targets): Autism, septic shock and eosinophilic esophagitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 430 |
|---|---|
| UniProt accession | Q9H8G1 |
| Gene | ZNF430 |
| Organism | Homo sapiens |
| Length | 570 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- Autism · score 0.01
- septic shock · score 0.01
- eosinophilic esophagitis · score 0.00
- spina bifida · score 0.00
- invasive breast ductal carcinoma · score 0.00
- pulmonary arterial hypertension · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8G1-F1 | alphafold | PREDICTED | 70.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8G1.
Amino-acid sequence (570 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF430?
The strongest Open Targets associations for ZNF430 are Autism, septic shock, eosinophilic esophagitis, spina bifida and invasive breast ductal carcinoma.
How long is the ZNF430 protein?
The Homo sapiens ZNF430 protein (UniProt Q9H8G1) is 570 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8G1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8G1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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