Caspase activity and apoptosis inhibitor 1 (CAAP1)
Homo sapiens — UniProt Q9H8G2
Data last refreshed: (UniProt release unknown)
Key facts
Caspase activity and apoptosis inhibitor 1 (CAAP1) is a protein from Homo sapiens identified by UniProt accession Q9H8G2, 361 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9H8G2; gene symbol CAAP1.
- Organism: Homo sapiens.
- Length: 361 amino acids.
- Top disease associations (Open Targets): protein measurement, wellbeing measurement and neuroticism measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Caspase activity and apoptosis inhibitor 1 |
|---|---|
| UniProt accession | Q9H8G2 |
| Gene | CAAP1 |
| Organism | Homo sapiens |
| Length | 361 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- wellbeing measurement · score 0.30
- neuroticism measurement · score 0.15
- depressive symptom measurement · score 0.15
- PHF-tau measurement · score 0.10
- asthma · score 0.02
- blood protein measurement · score 0.02
- external ear disease · score 0.02
- cancer · score 0.02
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8G2-F1 | alphafold | PREDICTED | 61.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8G2.
Amino-acid sequence (361 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAAP1?
The strongest Open Targets associations for CAAP1 are protein measurement, wellbeing measurement, neuroticism measurement, depressive symptom measurement and PHF-tau measurement.
How long is the CAAP1 protein?
The Homo sapiens CAAP1 protein (UniProt Q9H8G2) is 361 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8G2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8G2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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