Nucleolar protein 11 (NOL11)
Homo sapiens — UniProt Q9H8H0
Data last refreshed: (UniProt release unknown)
Key facts
Nucleolar protein 11 (NOL11) is a protein from Homo sapiens identified by UniProt accession Q9H8H0, 719 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9H8H0; gene symbol NOL11.
- Organism: Homo sapiens.
- Length: 719 amino acids.
- Top disease associations (Open Targets): mean platelet volume, metabolite measurement and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleolar protein 11 |
|---|---|
| UniProt accession | Q9H8H0 |
| Gene | NOL11 |
| Organism | Homo sapiens |
| Length | 719 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.33
- metabolite measurement · score 0.20
- type 2 diabetes mellitus · score 0.09
- rib fracture · score 0.07
- blood urea nitrogen measurement · score 0.07
- HbA1c measurement · score 0.06
- gut microbiome measurement · score 0.06
- serum urea measurement · score 0.06
- prurigo · score 0.04
- drug use measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8H0-F1 | alphafold | PREDICTED | 78.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8H0.
Amino-acid sequence (719 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOL11?
The strongest Open Targets associations for NOL11 are mean platelet volume, metabolite measurement, type 2 diabetes mellitus, rib fracture and blood urea nitrogen measurement.
How long is the NOL11 protein?
The Homo sapiens NOL11 protein (UniProt Q9H8H0) is 719 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8H0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8H0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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