MANSC domain-containing protein 1 (MANSC1)
Homo sapiens — UniProt Q9H8J5
Data last refreshed: (UniProt release unknown)
Key facts
MANSC domain-containing protein 1 (MANSC1) is a protein from Homo sapiens identified by UniProt accession Q9H8J5, 431 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q9H8J5; gene symbol MANSC1.
- Organism: Homo sapiens.
- Length: 431 amino acids.
- Top disease associations (Open Targets): blood protein measurement, urate measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MANSC domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H8J5 |
| Gene | MANSC1 |
| Organism | Homo sapiens |
| Length | 431 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.36
- urate measurement · score 0.33
- bone density · score 0.33
- cerebrospinal fluid biomarker measurement · score 0.29
- body height · score 0.19
- genetic disorder · score 0.12
- aspartate aminotransferase measurement · score 0.08
- basophil count · score 0.06
- lymphocyte percentage of leukocytes · score 0.05
- lean body mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8J5-F1 | alphafold | PREDICTED | 56.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8J5.
Amino-acid sequence (431 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MANSC1?
The strongest Open Targets associations for MANSC1 are blood protein measurement, urate measurement, bone density, cerebrospinal fluid biomarker measurement and body height.
How long is the MANSC1 protein?
The Homo sapiens MANSC1 protein (UniProt Q9H8J5) is 431 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8J5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8J5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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