ATPase PAAT (PAAT)
Homo sapiens — UniProt Q9H8K7
Data last refreshed: (UniProt release unknown)
Key facts
ATPase PAAT (PAAT) is a protein from Homo sapiens identified by UniProt accession Q9H8K7, 445 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9H8K7; gene symbol PAAT.
- Organism: Homo sapiens.
- Length: 445 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, low density lipoprotein cholesterol measurement and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATPase PAAT |
|---|---|
| UniProt accession | Q9H8K7 |
| Gene | PAAT |
| Organism | Homo sapiens |
| Length | 445 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.44
- low density lipoprotein cholesterol measurement · score 0.41
- mean corpuscular hemoglobin concentration · score 0.39
- mean corpuscular volume · score 0.38
- apolipoprotein B measurement · score 0.33
- alcohol drinking · score 0.32
- mean reticulocyte volume · score 0.30
- total cholesterol measurement · score 0.30
- reticulocyte count · score 0.28
- reticulocyte measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8K7-F1 | alphafold | PREDICTED | 65.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8K7.
Amino-acid sequence (445 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAAT?
The strongest Open Targets associations for PAAT are Red cell distribution width, low density lipoprotein cholesterol measurement, mean corpuscular hemoglobin concentration, mean corpuscular volume and apolipoprotein B measurement.
How long is the PAAT protein?
The Homo sapiens PAAT protein (UniProt Q9H8K7) is 445 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8K7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8K7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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