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Multimerin-2 (MMRN2)

Homo sapiens — UniProt Q9H8L6

Gene: MMRN2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Multimerin-2 (MMRN2) is a protein from Homo sapiens identified by UniProt accession Q9H8L6, 949 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

  • UniProt accession: Q9H8L6; gene symbol MMRN2.
  • Organism: Homo sapiens.
  • Length: 949 amino acids.
  • Top disease associations (Open Targets): neoplasm, lung adenocarcinoma and proliferative vitreoretinopathy.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMultimerin-2
UniProt accessionQ9H8L6
GeneMMRN2
OrganismHomo sapiens
Length949 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (41)

Diseases linked to this target (Open Targets).

  • neoplasm · score 0.06
  • lung adenocarcinoma · score 0.04
  • proliferative vitreoretinopathy · score 0.03
  • exudative vitreoretinopathy 2, X-linked · score 0.03
  • Familial exudative vitreoretinopathy · score 0.03
  • body height · score 0.02
  • non-small cell lung carcinoma · score 0.02
  • age-related macular degeneration · score 0.02
  • systemic scleroderma · score 0.02
  • COVID-19 · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H8L6-F1alphafoldPREDICTED65.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8L6.

Amino-acid sequence (949 residues)

MILSLLFSLG GPLGWGLLGA WAQASSTSLS DLQSSRTPGV WKAEAEDTGK DPVGRNWCPY PMSKLVTLLA LCKTEKFLIH SQQPCPQGAP DCQKVKVMYR MAHKPVYQVK QKVLTSLAWR CCPGYTGPNC EHHDSMAIPE PADPGDSHQE PQDGPVSFKP GHLAAVINEV EVQQEQQEHL LGDLQNDVHR VADSLPGLWK ALPGNLTAAV MEANQTGHEF PDRSLEQVLL PHVDTFLQVH FSPIWRSFNQ SLHSLTQAIR NLSLDVEANR QAISRVQDSA VARADFQELG AKFEAKVQEN TQRVGQLRQD VEDRLHAQHF TLHRSISELQ ADVDTKLKRL HKAQEAPGTN GSLVLATPGA GARPEPDSLQ ARLGQLQRNL SELHMTTARR EEELQYTLED MRATLTRHVD EIKELYSESD ETFDQISKVE RQVEELQVNH TALRELRVIL MEKSLIMEEN KEEVERQLLE LNLTLQHLQG GHADLIKYVK DCNCQKLYLD LDVIREGQRD ATRALEETQV SLDERRQLDG SSLQALQNAV DAVSLAVDAH KAEGERARAA TSRLRSQVQA LDDEVGALKA AAAEARHEVR QLHSAFAALL EDALRHEAVL AALFGEEVLE EMSEQTPGPL PLSYEQIRVA LQDAASGLQE QALGWDELAA RVTALEQASE PPRPAEHLEP SHDAGREEAA TTALAGLARE LQSLSNDVKN VGRCCEAEAG AGAASLNASL HGLHNALFAT QRSLEQHQRL FHSLFGNFQG LMEANVSLDL GKLQTMLSRK GKKQQKDLEA PRKRDKKEAE PLVDIRVTGP VPGALGAALW EAGSPVAFYA SFSEGTAALQ TVKFNTTYIN IGSSYFPEHG YFRAPERGVY LFAVSVEFGP GPGTGQLVFG GHHRTPVCTT GQGSGSTATV FAMAELQKGE RVWFELTQGS ITKRSLSGTA FGGFLMFKT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MMRN2?

The strongest Open Targets associations for MMRN2 are neoplasm, lung adenocarcinoma, proliferative vitreoretinopathy, exudative vitreoretinopathy 2, X-linked and Familial exudative vitreoretinopathy.

How long is the MMRN2 protein?

The Homo sapiens MMRN2 protein (UniProt Q9H8L6) is 949 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H8L6
GeneMMRN2
OrganismHomo sapiens
Length949
Binders0
Diseases41
View on UniProt