Coenzyme Q-binding protein COQ10 homolog B, mitochondrial (COQ10B)
Homo sapiens — UniProt Q9H8M1
Data last refreshed: (UniProt release unknown)
Key facts
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial (COQ10B) is a protein from Homo sapiens identified by UniProt accession Q9H8M1, 238 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9H8M1; gene symbol COQ10B.
- Organism: Homo sapiens.
- Length: 238 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, chronotype measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coenzyme Q-binding protein COQ10 homolog B, mitochondrial |
|---|---|
| UniProt accession | Q9H8M1 |
| Gene | COQ10B |
| Organism | Homo sapiens |
| Length | 238 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- chronotype measurement · score 0.18
- mean corpuscular volume · score 0.18
- Alzheimer disease · score 0.17
- multiple sclerosis · score 0.17
- lysosomal storage disease · score 0.17
- Parkinson disease · score 0.17
- circadian rhythm · score 0.15
- schizophrenia · score 0.15
- body height · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8M1-F1 | alphafold | PREDICTED | 78.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8M1.
Amino-acid sequence (238 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COQ10B?
The strongest Open Targets associations for COQ10B are neurodegenerative disease, chronotype measurement, mean corpuscular volume, Alzheimer disease and multiple sclerosis.
How long is the COQ10B protein?
The Homo sapiens COQ10B protein (UniProt Q9H8M1) is 238 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8M1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8M1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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