Bromodomain-containing protein 9 (BRD9)
Homo sapiens — UniProt Q9H8M2
Data last refreshed: (UniProt release unknown)
Key facts
Bromodomain-containing protein 9 (BRD9) is a protein from Homo sapiens identified by UniProt accession Q9H8M2, 597 residues long. MolForge cross-references it against 1 known binders and 140 disease associations.
- UniProt accession: Q9H8M2; gene symbol BRD9.
- Organism: Homo sapiens.
- Length: 597 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, acute myeloid leukemia and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Bromodomain-containing protein 9 |
|---|---|
| UniProt accession | Q9H8M2 |
| Gene | BRD9 |
| Organism | Homo sapiens |
| Length | 597 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (140)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- acute myeloid leukemia · score 0.11
- cancer · score 0.11
- Miyoshi myopathy · score 0.10
- hepatocellular carcinoma · score 0.08
- Ochoa syndrome · score 0.08
- neoplasm · score 0.08
- synovial sarcoma · score 0.08
- gastrointestinal stromal tumor · score 0.08
- acute lymphoblastic leukemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8M2-F1 | alphafold | PREDICTED | 62.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8M2.
Amino-acid sequence (597 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BRD9?
The strongest Open Targets associations for BRD9 are neurodegenerative disease, acute myeloid leukemia, cancer, Miyoshi myopathy and hepatocellular carcinoma.
How long is the BRD9 protein?
The Homo sapiens BRD9 protein (UniProt Q9H8M2) is 597 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8M2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8M2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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