Ubiquitin carboxyl-terminal hydrolase MINDY-3 (MINDY3)
Homo sapiens — UniProt Q9H8M7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase MINDY-3 (MINDY3) is a protein from Homo sapiens identified by UniProt accession Q9H8M7, 445 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H8M7; gene symbol MINDY3.
- Organism: Homo sapiens.
- Length: 445 amino acids.
- Top disease associations (Open Targets): reticulocyte count, mean reticulocyte volume and Abnormal systemic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase MINDY-3 |
|---|---|
| UniProt accession | Q9H8M7 |
| Gene | MINDY3 |
| Organism | Homo sapiens |
| Length | 445 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.46
- mean reticulocyte volume · score 0.34
- Abnormal systemic blood pressure · score 0.33
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.28
- PHF-tau measurement · score 0.10
- protein measurement · score 0.09
- forced expiratory volume · score 0.05
- FEV/FVC ratio · score 0.03
- peak expiratory flow · score 0.03
- non-small cell lung carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8M7-F1 | alphafold | PREDICTED | 87.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8M7.
Amino-acid sequence (445 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MINDY3?
The strongest Open Targets associations for MINDY3 are reticulocyte count, mean reticulocyte volume, Abnormal systemic blood pressure, t-tau:beta-amyloid 1-42 ratio measurement and PHF-tau measurement.
How long is the MINDY3 protein?
The Homo sapiens MINDY3 protein (UniProt Q9H8M7) is 445 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8M7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8M7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.