Protein eva-1 homolog A (EVA1A)
Homo sapiens — UniProt Q9H8M9
Data last refreshed: (UniProt release unknown)
Key facts
Protein eva-1 homolog A (EVA1A) is a protein from Homo sapiens identified by UniProt accession Q9H8M9, 152 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: Q9H8M9; gene symbol EVA1A.
- Organism: Homo sapiens.
- Length: 152 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, serum gamma-glutamyl transferase measurement and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein eva-1 homolog A |
|---|---|
| UniProt accession | Q9H8M9 |
| Gene | EVA1A |
| Organism | Homo sapiens |
| Length | 152 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.44
- serum gamma-glutamyl transferase measurement · score 0.40
- serum alanine aminotransferase measurement · score 0.32
- lymphocyte count · score 0.31
- hepatocellular carcinoma · score 0.10
- papillary thyroid carcinoma · score 0.08
- Brugada syndrome · score 0.08
- familial atrial fibrillation · score 0.07
- Familial progressive cardiac conduction defect · score 0.07
- Romano-Ward syndrome · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8M9-F1 | alphafold | PREDICTED | 64.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8M9.
Amino-acid sequence (152 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EVA1A?
The strongest Open Targets associations for EVA1A are heel bone mineral density, serum gamma-glutamyl transferase measurement, serum alanine aminotransferase measurement, lymphocyte count and hepatocellular carcinoma.
How long is the EVA1A protein?
The Homo sapiens EVA1A protein (UniProt Q9H8M9) is 152 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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