Zinc finger protein 395 (ZNF395)
Homo sapiens — UniProt Q9H8N7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 395 (ZNF395) is a protein from Homo sapiens identified by UniProt accession Q9H8N7, 513 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q9H8N7; gene symbol ZNF395.
- Organism: Homo sapiens.
- Length: 513 amino acids.
- Top disease associations (Open Targets): non-small cell lung carcinoma, birth weight and chondrosarcoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 395 |
|---|---|
| UniProt accession | Q9H8N7 |
| Gene | ZNF395 |
| Organism | Homo sapiens |
| Length | 513 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- non-small cell lung carcinoma · score 0.37
- birth weight · score 0.12
- chondrosarcoma · score 0.07
- Brugada syndrome · score 0.06
- Arrhythmogenic right ventricular dysplasia · score 0.05
- Romano-Ward syndrome · score 0.05
- familial atrial fibrillation · score 0.05
- body mass index · score 0.05
- Familial short QT syndrome · score 0.05
- cancer · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8N7-F1 | alphafold | PREDICTED | 58.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8N7.
Amino-acid sequence (513 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF395?
The strongest Open Targets associations for ZNF395 are non-small cell lung carcinoma, birth weight, chondrosarcoma, Brugada syndrome and Arrhythmogenic right ventricular dysplasia.
How long is the ZNF395 protein?
The Homo sapiens ZNF395 protein (UniProt Q9H8N7) is 513 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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