MOB kinase activator 1A (MOB1A)
Homo sapiens — UniProt Q9H8S9
Data last refreshed: (UniProt release unknown)
Key facts
MOB kinase activator 1A (MOB1A) is a protein from Homo sapiens identified by UniProt accession Q9H8S9, 216 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9H8S9; gene symbol MOB1A.
- Organism: Homo sapiens.
- Length: 216 amino acids.
- Top disease associations (Open Targets): Romano-Ward syndrome, Familial short QT syndrome and Brugada syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MOB kinase activator 1A |
|---|---|
| UniProt accession | Q9H8S9 |
| Gene | MOB1A |
| Organism | Homo sapiens |
| Length | 216 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- Romano-Ward syndrome · score 0.08
- Familial short QT syndrome · score 0.07
- Brugada syndrome · score 0.07
- familial atrial fibrillation · score 0.06
- long QT syndrome 11 · score 0.06
- Arrhythmogenic right ventricular dysplasia · score 0.06
- Brugada syndrome 9 · score 0.05
- long QT syndrome 14 · score 0.05
- Jervell and Lange-Nielsen syndrome 1 · score 0.05
- long QT syndrome 1 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8S9-F1 | alphafold | PREDICTED | 88.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8S9.
Amino-acid sequence (216 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOB1A?
The strongest Open Targets associations for MOB1A are Romano-Ward syndrome, Familial short QT syndrome, Brugada syndrome, familial atrial fibrillation and long QT syndrome 11.
How long is the MOB1A protein?
The Homo sapiens MOB1A protein (UniProt Q9H8S9) is 216 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8S9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8S9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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