AKT-interacting protein (AKTIP)
Homo sapiens — UniProt Q9H8T0
Data last refreshed: (UniProt release unknown)
Key facts
AKT-interacting protein (AKTIP) is a protein from Homo sapiens identified by UniProt accession Q9H8T0, 292 residues long. MolForge cross-references it against 0 known binders and 147 disease associations.
- UniProt accession: Q9H8T0; gene symbol AKTIP.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): BMI-adjusted hip circumference, self reported educational attainment and cognitive function measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | AKT-interacting protein |
|---|---|
| UniProt accession | Q9H8T0 |
| Gene | AKTIP |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (147)
Diseases linked to this target (Open Targets).
- BMI-adjusted hip circumference · score 0.24
- self reported educational attainment · score 0.18
- cognitive function measurement · score 0.17
- BMI-adjusted waist-hip ratio · score 0.17
- heart rate · score 0.16
- intelligence · score 0.16
- waist-hip ratio · score 0.15
- health study participation · score 0.13
- mathematical ability · score 0.13
- ovarian dysfunction · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8T0-F1 | alphafold | PREDICTED | 77.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8T0.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AKTIP?
The strongest Open Targets associations for AKTIP are BMI-adjusted hip circumference, self reported educational attainment, cognitive function measurement, BMI-adjusted waist-hip ratio and heart rate.
How long is the AKTIP protein?
The Homo sapiens AKTIP protein (UniProt Q9H8T0) is 292 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8T0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8T0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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