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AN1-type zinc finger protein 3 (ZFAND3)

Homo sapiens — UniProt Q9H8U3

Gene: ZFAND3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

AN1-type zinc finger protein 3 (ZFAND3) is a protein from Homo sapiens identified by UniProt accession Q9H8U3, 227 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

  • UniProt accession: Q9H8U3; gene symbol ZFAND3.
  • Organism: Homo sapiens.
  • Length: 227 amino acids.
  • Top disease associations (Open Targets): body height, balding measurement and hair shape measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAN1-type zinc finger protein 3
UniProt accessionQ9H8U3
GeneZFAND3
OrganismHomo sapiens
Length227 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (30)

Diseases linked to this target (Open Targets).

  • body height · score 0.23
  • balding measurement · score 0.23
  • hair shape measurement · score 0.23
  • type 2 diabetes mellitus · score 0.19
  • arterial stiffness measurement · score 0.14
  • indoxyl sulfate measurement · score 0.10
  • neoplasm · score 0.08
  • glioblastoma multiforme · score 0.07
  • IGF-1 measurement · score 0.06
  • insulin like growth factor measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H8U3-F1alphafoldPREDICTED68.82—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8U3.

Amino-acid sequence (227 residues)

MGDAGSERSK APSLPPRCPC GFWGSSKTMN LCSKCFADFQ KKQPDDDSAP STSNSQSDLF SEETTSDNNN TSITTPTLSP SQQPLPTELN VTSPSKEECG PCTDTAHVSL ITPTKRSCGT DSQSENEASP VKRPRLLENT ERSEETSRSK QKSRRRCFQC QTKLELVQQE LGSCRCGYVF CMLHRLPEQH DCTFDHMGRG REEAIMKMVK LDRKVGRSCQ RIGEGCS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZFAND3?

The strongest Open Targets associations for ZFAND3 are body height, balding measurement, hair shape measurement, type 2 diabetes mellitus and arterial stiffness measurement.

How long is the ZFAND3 protein?

The Homo sapiens ZFAND3 protein (UniProt Q9H8U3) is 227 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H8U3
GeneZFAND3
OrganismHomo sapiens
Length227
Binders0
Diseases30
View on UniProt