Protein ECT2 (ECT2)
Homo sapiens — UniProt Q9H8V3
Data last refreshed: (UniProt release unknown)
Key facts
Protein ECT2 (ECT2) is a protein from Homo sapiens identified by UniProt accession Q9H8V3, 914 residues long. MolForge cross-references it against 0 known binders and 188 disease associations.
- UniProt accession: Q9H8V3; gene symbol ECT2.
- Organism: Homo sapiens.
- Length: 914 amino acids.
- Top disease associations (Open Targets): platelet count, neurodegenerative disease and TNF-related apoptosis-inducing ligand measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ECT2 |
|---|---|
| UniProt accession | Q9H8V3 |
| Gene | ECT2 |
| Organism | Homo sapiens |
| Length | 914 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (188)
Diseases linked to this target (Open Targets).
- platelet count · score 0.44
- neurodegenerative disease · score 0.32
- TNF-related apoptosis-inducing ligand measurement · score 0.24
- breast adenocarcinoma · score 0.18
- clavicle fracture · score 0.16
- platelet crit · score 0.13
- glioblastoma multiforme · score 0.12
- neoplasm · score 0.11
- lung adenocarcinoma · score 0.10
- non-small cell lung carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8V3-F1 | alphafold | PREDICTED | 70.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8V3.
Amino-acid sequence (914 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ECT2?
The strongest Open Targets associations for ECT2 are platelet count, neurodegenerative disease, TNF-related apoptosis-inducing ligand measurement, breast adenocarcinoma and clavicle fracture.
How long is the ECT2 protein?
The Homo sapiens ECT2 protein (UniProt Q9H8V3) is 914 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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