Inositol-pentakisphosphate 2-kinase (IPPK)
Homo sapiens — UniProt Q9H8X2
Data last refreshed: (UniProt release unknown)
Key facts
Inositol-pentakisphosphate 2-kinase (IPPK) is a protein from Homo sapiens identified by UniProt accession Q9H8X2, 491 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9H8X2; gene symbol IPPK.
- Organism: Homo sapiens.
- Length: 491 amino acids.
- Top disease associations (Open Targets): body height, blood protein measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inositol-pentakisphosphate 2-kinase |
|---|---|
| UniProt accession | Q9H8X2 |
| Gene | IPPK |
| Organism | Homo sapiens |
| Length | 491 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- blood protein measurement · score 0.31
- platelet count · score 0.28
- high density lipoprotein cholesterol measurement · score 0.25
- lymphocyte count · score 0.25
- neutrophil count · score 0.24
- leukocyte count · score 0.24
- BMI-adjusted waist-hip ratio · score 0.20
- myeloid white cell count · score 0.19
- triglyceride measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8X2-F1 | alphafold | PREDICTED | 88.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8X2.
Amino-acid sequence (491 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IPPK?
The strongest Open Targets associations for IPPK are body height, blood protein measurement, platelet count, high density lipoprotein cholesterol measurement and lymphocyte count.
How long is the IPPK protein?
The Homo sapiens IPPK protein (UniProt Q9H8X2) is 491 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8X2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8X2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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