Palmitoyltransferase ZDHHC11 (ZDHHC11)
Homo sapiens — UniProt Q9H8X9
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC11 (ZDHHC11) is a protein from Homo sapiens identified by UniProt accession Q9H8X9, 412 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9H8X9; gene symbol ZDHHC11.
- Organism: Homo sapiens.
- Length: 412 amino acids.
- Top disease associations (Open Targets): COVID-19, neurodegenerative disease and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC11 |
|---|---|
| UniProt accession | Q9H8X9 |
| Gene | ZDHHC11 |
| Organism | Homo sapiens |
| Length | 412 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.37
- neurodegenerative disease · score 0.28
- Red cell distribution width · score 0.19
- age at onset · score 0.13
- Myopia · score 0.13
- FEV/FVC ratio · score 0.09
- upper extremity fracture · score 0.07
- Zika virus infectious disease · score 0.07
- diffuse large B-cell lymphoma · score 0.07
- deafness · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8X9-F1 | alphafold | PREDICTED | 73.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8X9.
Amino-acid sequence (412 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC11?
The strongest Open Targets associations for ZDHHC11 are COVID-19, neurodegenerative disease, Red cell distribution width, age at onset and Myopia.
How long is the ZDHHC11 protein?
The Homo sapiens ZDHHC11 protein (UniProt Q9H8X9) is 412 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8X9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8X9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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