Vertnin (VRTN)
Homo sapiens — UniProt Q9H8Y1
Data last refreshed: (UniProt release unknown)
Key facts
Vertnin (VRTN) is a protein from Homo sapiens identified by UniProt accession Q9H8Y1, 702 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9H8Y1; gene symbol VRTN.
- Organism: Homo sapiens.
- Length: 702 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, vital capacity and forced expiratory volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vertnin |
|---|---|
| UniProt accession | Q9H8Y1 |
| Gene | VRTN |
| Organism | Homo sapiens |
| Length | 702 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.56
- vital capacity · score 0.46
- forced expiratory volume · score 0.43
- PHF-tau measurement · score 0.31
- sitting height measurement · score 0.19
- lysosomal storage disease · score 0.10
- autosomal recessive spondylocostal dysostosis · score 0.07
- autosomal dominant brachyolmia · score 0.06
- autosomal dominant spondylocostal dysostosis · score 0.05
- blood protein measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8Y1-F1 | alphafold | PREDICTED | 68.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8Y1.
Amino-acid sequence (702 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VRTN?
The strongest Open Targets associations for VRTN are neurodegenerative disease, vital capacity, forced expiratory volume, PHF-tau measurement and sitting height measurement.
How long is the VRTN protein?
The Homo sapiens VRTN protein (UniProt Q9H8Y1) is 702 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8Y1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8Y1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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