Golgi reassembly-stacking protein 2 (GORASP2)
Homo sapiens — UniProt Q9H8Y8
Data last refreshed: (UniProt release unknown)
Key facts
Golgi reassembly-stacking protein 2 (GORASP2) is a protein from Homo sapiens identified by UniProt accession Q9H8Y8, 452 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.
- UniProt accession: Q9H8Y8; gene symbol GORASP2.
- Organism: Homo sapiens.
- Length: 452 amino acids.
- Top disease associations (Open Targets): body height, age at menopause and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi reassembly-stacking protein 2 |
|---|---|
| UniProt accession | Q9H8Y8 |
| Gene | GORASP2 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- body height · score 0.25
- age at menopause · score 0.23
- mean platelet volume · score 0.20
- platelet count · score 0.19
- type 1 diabetes mellitus · score 0.18
- alkaline phosphatase measurement · score 0.17
- mathematical ability · score 0.16
- platelet component distribution width · score 0.16
- appendicular lean mass · score 0.14
- lean body mass · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H8Y8-F1 | alphafold | PREDICTED | 64.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H8Y8.
Amino-acid sequence (452 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GORASP2?
The strongest Open Targets associations for GORASP2 are body height, age at menopause, mean platelet volume, platelet count and type 1 diabetes mellitus.
How long is the GORASP2 protein?
The Homo sapiens GORASP2 protein (UniProt Q9H8Y8) is 452 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H8Y8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H8Y8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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