Protein zwilch homolog (ZWILCH)
Homo sapiens — UniProt Q9H900
Data last refreshed: (UniProt release unknown)
Key facts
Protein zwilch homolog (ZWILCH) is a protein from Homo sapiens identified by UniProt accession Q9H900, 591 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q9H900; gene symbol ZWILCH.
- Organism: Homo sapiens.
- Length: 591 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein zwilch homolog |
|---|---|
| UniProt accession | Q9H900 |
| Gene | ZWILCH |
| Organism | Homo sapiens |
| Length | 591 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- sex hormone-binding globulin measurement · score 0.23
- mean corpuscular volume · score 0.19
- body mass index · score 0.14
- Testicular Germ Cell Tumor · score 0.11
- mean platelet volume · score 0.10
- mean corpuscular hemoglobin · score 0.09
- prostate carcinoma · score 0.09
- erythrocyte count · score 0.09
- IGF-1 measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H900-F1 | alphafold | PREDICTED | 82.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H900.
Amino-acid sequence (591 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZWILCH?
The strongest Open Targets associations for ZWILCH are neurodegenerative disease, sex hormone-binding globulin measurement, mean corpuscular volume, body mass index and Testicular Germ Cell Tumor.
How long is the ZWILCH protein?
The Homo sapiens ZWILCH protein (UniProt Q9H900) is 591 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H900 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H900 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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