Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2)
Homo sapiens — UniProt Q9H939
Data last refreshed: (UniProt release unknown)
Key facts
Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2) is a protein from Homo sapiens identified by UniProt accession Q9H939, 334 residues long. MolForge cross-references it against 0 known binders and 193 disease associations.
- UniProt accession: Q9H939; gene symbol PSTPIP2.
- Organism: Homo sapiens.
- Length: 334 amino acids.
- Top disease associations (Open Targets): platelet count, neurodegenerative disease and drug use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline-serine-threonine phosphatase-interacting protein 2 |
|---|---|
| UniProt accession | Q9H939 |
| Gene | PSTPIP2 |
| Organism | Homo sapiens |
| Length | 334 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (193)
Diseases linked to this target (Open Targets).
- platelet count · score 0.40
- neurodegenerative disease · score 0.37
- drug use measurement · score 0.29
- platelet crit · score 0.28
- mean corpuscular hemoglobin · score 0.16
- eosinophil count · score 0.16
- chilblain lupus · score 0.07
- Red cell distribution width · score 0.06
- mean corpuscular volume · score 0.06
- Balkan nephropathy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H939-F1 | alphafold | PREDICTED | 89.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H939.
Amino-acid sequence (334 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSTPIP2?
The strongest Open Targets associations for PSTPIP2 are platelet count, neurodegenerative disease, drug use measurement, platelet crit and mean corpuscular hemoglobin.
How long is the PSTPIP2 protein?
The Homo sapiens PSTPIP2 protein (UniProt Q9H939) is 334 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H939 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H939 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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