WD repeat-containing protein 76 (WDR76)
Homo sapiens — UniProt Q9H967
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 76 (WDR76) is a protein from Homo sapiens identified by UniProt accession Q9H967, 626 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9H967; gene symbol WDR76.
- Organism: Homo sapiens.
- Length: 626 amino acids.
- Top disease associations (Open Targets): neoplasm, hepatocellular carcinoma and Obesity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 76 |
|---|---|
| UniProt accession | Q9H967 |
| Gene | WDR76 |
| Organism | Homo sapiens |
| Length | 626 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.06
- Obesity · score 0.05
- diastolic blood pressure · score 0.05
- blood protein measurement · score 0.04
- lung adenocarcinoma · score 0.04
- mathematical ability · score 0.04
- Hepatic steatosis · score 0.04
- triglyceride measurement · score 0.04
- hemoglobin A1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H967-F1 | alphafold | PREDICTED | 75.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H967.
Amino-acid sequence (626 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR76?
The strongest Open Targets associations for WDR76 are neoplasm, hepatocellular carcinoma, Obesity, diastolic blood pressure and blood protein measurement.
How long is the WDR76 protein?
The Homo sapiens WDR76 protein (UniProt Q9H967) is 626 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H967 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H967 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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