Queuine tRNA-ribosyltransferase accessory subunit 2 (QTRT2)
Homo sapiens — UniProt Q9H974
Data last refreshed: (UniProt release unknown)
Key facts
Queuine tRNA-ribosyltransferase accessory subunit 2 (QTRT2) is a protein from Homo sapiens identified by UniProt accession Q9H974, 415 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q9H974; gene symbol QTRT2.
- Organism: Homo sapiens.
- Length: 415 amino acids.
- Top disease associations (Open Targets): HIV infection, Cognitive impairment and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Queuine tRNA-ribosyltransferase accessory subunit 2 |
|---|---|
| UniProt accession | Q9H974 |
| Gene | QTRT2 |
| Organism | Homo sapiens |
| Length | 415 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.08
- Cognitive impairment · score 0.00
- cancer · score 0.00
- glioblastoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H974-F1 | alphafold | PREDICTED | 89.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H974.
Amino-acid sequence (415 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with QTRT2?
The strongest Open Targets associations for QTRT2 are HIV infection, Cognitive impairment, cancer and glioblastoma.
How long is the QTRT2 protein?
The Homo sapiens QTRT2 protein (UniProt Q9H974) is 415 amino acids long.
Browse: Targets: Q · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H974 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H974 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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